LSBio
Monoclonal Mouse anti-Human IL6ST / CD130 / gp130 Antibody (clone B-T2)

Monoclonal Mouse anti-Human IL6ST / CD130 / gp130 Antibody (clone B-T2)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry
Reactivity:Human
Format:Liquid
See all Human IL6ST / CD130 / gp130 antibodies →
$286.00each
Catalog Number: LS-C43306-0.1

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Overview

Description
Gp130 antibody LS-C43306 is an unconjugated mouse monoclonal antibody to human gp130 (IL6ST / CD130). Validated for ELISA and Flow.
Application
ELISA, FC
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD130 | CD130 antigen | IL-6R subunit beta | IL-6 receptor subunit beta | Membrane glycoprotein gp130 | Membrane glycoprotein 130 | IL-6RB | IL6ST | CDW130 | gp130 | IL-6R-beta
UniProt Number
P40189
SwissProt
P40189

Target

Target
Human IL6ST / CD130 / gp130
Antigen Species
Hu
Epitope
Recognizes soluble and membrane bound gp130 receptor, also known as CD130, Interleukin-6 receptor subunit beta, Oncostatin-M receptor subunit alpha or Interleukin-6 signal transducer. CD130 is a 918 amino acid, ~130 kD single pass type-1 transmembrane glycoprotein containing a single and multiple domains. CD130 can be cleaved to form a monomeric soluble ~100 kD form of the receptor detectable in plasma and other biologic fluids where it acts as an IL-6 antagonist. Binds to an epitope dependent at least partially on the presence of the Ig-like domain. Has been reported to block receptor activity and inhibit IL-6 induced proliferation of XG1 cells and IL-27 mediated proliferation of naive CD4+ T cells,.
Gene Name
IL6ST

Antibody

Host Species
Ms
Clonality
Monoclonal
Clone
B-T2
Isotype
IgG1

Immunogen

Immunogen
Natural soluble gp130 receptor.

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
IEX

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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