IF staining of U937 cells.
IL6R / IL6 Receptor Antibody (IL-6 receptor, clone rhPM-1 (Tocilizumab))
Primary AntibodyLSBio Guarantee
| Antibody: | Human Recombinant Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Inhibitor / Activator Screening |
| Reactivity: | Human |
| Format: | Liquid |
$551.00each
Catalog Number: LS-C777555-0.2
Catalog Number: LS-C777555
For bulk orders or custom formulations:
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- Description
- This IL6R / IL6 Receptor antibody is an unconjugated Human/Human chimeric recombinant monoclonal antibody. Validated for ELISA and Inhb.
- Application
- ELISA, Inh / Act Screen
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CD126 | gp80 | IL-6R subunit alpha | IL-6R-alpha | IL-6RA | IL6Q | IL-6 receptor subunit alpha | IL-6R 1 | IL-6R-1 | Interleukin 6 receptor | Membrane glycoprotein 80 | CD126 antigen | IL6R | IL6RA | IL6RQ
- UniProt Number
- P08887
- NCBI GenBank
- NM_000565 | NP_000556.1
- SwissProt
- P08887
Target
- Target
- Human IL6R / IL6 Receptor
- Antigen Species
- Human
- Epitope
- Tocilizumab binds specifically to both the membrane bound and soluble forms of human IL-6R. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.
- Gene Name
- IL6R
Antibody
- Host Species
- Human
- Clonality
- Recombinant Monoclonal
- Clone
- rhPM-1 (Tocilizumab)
- Isotype
- IgG1
- Light Chain
- Kappa Light Chain
- Origin Species
- Human
Immunogen
- Immunogen
- This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.02% ProClin™ 300.
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
- Recommended Storage Buffer
- PBS