LSBio
IL-10 Antibody (clone IL10/2651R)

Formalin-fixed, paraffin-embedded human Endo-cervical Carcinoma stained with Interleukin 10 Recombinant Rabbit Monoclonal Antibody (IL10/2651R).

IL-10 Antibody (clone IL10/2651R)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Human IL-10 antibodies →
$379.00each
Catalog Number: LS-C751212-20

For bulk orders or custom formulations:

Request a Quote

Overview

Description
IL-10 antibody LS-C751212 is an unconjugated rabbit recombinant monoclonal antibody to human IL-10. Validated for IHC. Cited in 1 publication.
Application
IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CSIF | GVHDS | IL-10 | IL10 | IL10A | Interleukin-10 | Interleukin 10 | TGIF
Recommended Dilution: IHC-P
1 - 2 µg/ml
UniProt Number
P22301
SwissProt
P22301

Target

Target
Human IL-10
Antigen Species
Human
Epitope
Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Gene Name
IL10

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
IL10/2651R
Isotype
IgG
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human Interleukin 10 (IL10) protein. Antigen Molecular Weight: 20 kDa (Monomer) - 37 kDa (Dimer)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
1 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
1 mM PBS
Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-? production in chronic rhinosinusitis with nasal polyps. Mitsuhiro Okano, Tazuko Fujiwara, Shin Kariya, Takaya Higaki, Sei-ichiro Makihara, Takenori Haruna, Yasuyuki Noyama, Takahisa Koyama, Ryotaro Omichi, Yorihisa Orita, Kentaro Miki, Kengo Kanai, Kazunori Nishizaki. Allergology international : official journal of the Japanese Society of Allergology. 2016 January;65:96-102. PubMed: 26666485

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.