SDC2 / Syndecan 2 Antibody
Catalog Number: LS-C817407-100
100 µL / $309.00
Antibody: Rabbit Polyclonal
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Paraffin
Reactivity: Human
Format: Liquid
Anti-SDC2 / Syndecan 2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IHC-plus™ SDC2 / Syndecan 2 Antibody (Internal)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$495.00each
Catalog Number: LS-B2981-50
Catalog Number: LS-B2981
For bulk orders or custom formulations:
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- Description
- Syndecan 2 antibody LS-B2981 is an unconjugated rabbit polyclonal antibody to human Syndecan 2 (SDC2) (Internal). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
- Application
- ELISA, IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CD362 | CD362 antigen | HSPG | HSPG1 | Fibroglycan | Syndecan proteoglycan 2 | SDC2 | SYND2 | Syndecan 2 | Syndecan-2
- Recommended Dilution: ELISA
- 0.1 - 1 µg/ml
- Recommended Dilution: IHC-P
- 5 µg/ml
- Recommended Dilution: WB
- 1 - 3 µg/ml
- UniProt Number
- P34741
- NCBI GenBank
- J04621
- SwissProt
- P34741
Target
- Target
- SDC2 / Syndecan 2
- Antigen Species
- Human
- Specificity
- Recognizes human syndecan-2 (fibroglycan). It recognizes the unglyconated form and may recognize the glyconated form. On Western Blots, it identifies a single band at ~22kD. An additional band at ~40kD may also be observed which may represent a glycanated form. Reactivity has been confirmed with human A-549 lung carcinoma, HEP-G2 hepatocellular carcinoma, HT-29 colorectal adenocarcinoma, K-562 chronic myelogenous leukemia-bone marrow, TF-1 erythroleukemia-bone marrow and U-2 OS osteosarcoma cell lysates.
- Epitope
- Recognizes human syndecan-2 (fibroglycan). It recognizes the unglyconated form and may recognize the glyconated form. On Western Blots, it identifies a single band at ~22kD. An additional band at ~40kD may also be observed which may represent a glycanated form. Reactivity has been confirmed with human A-549 lung carcinoma, HEP-G2 hepatocellular carcinoma, HT-29 colorectal adenocarcinoma, K-562 chronic myelogenous leukemia-bone marrow, TF-1 erythroleukemia-bone marrow and U-2 OS osteosarcoma cell lysates.
- Gene Name
- SDC2
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide derived from the internal region of human syndecan-2 (fibroglycan).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.09% Sodium Azide
- Concentration
- 0.25 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells. Multhaupt H, Couchman JR. Molecular cancer. Jan;14:15.
PubMed: 25623282 · PMC: PMC4326193
Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma. Waters AM, Stafman LL, Garner EF, Mruthyunjayappa S, Stewart JE, Friedman GK, Coleman JM, Markert JM, Gillespie GY, Beierle EA. Translational oncology. 2016;9:419-430.
PubMed: 27751346 · PMC: PMC5067929
N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA165<sub>-dependent neovascularization. Corti F, Wang Y, Rhodes JM, Atri D, Archer-Hartmann S, Zhang J, Zhuang ZW, Chen D, Wang T, Wang Z, Azadi P, Simons M. Nature communications. 2019 April;10:1562.
PubMed: 30952866 · PMC: PMC6450910
