CD27L / CD70 Antibody
Catalog Number: LS-C742771
2 sizes / from $341.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human
Format: Liquid
Anti-CD70 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
IHC-plus™ CD27L / CD70 Antibody (Internal)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$449.00each
Catalog Number: LS-A8809-50
Catalog Number: LS-A8809
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- Description
- CD70 antibody LS-A8809 is an unconjugated rabbit polyclonal antibody to human CD70 (CD27L) (Internal). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Predicted Reactivity
- Non-Human Primate
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CD27LG | CD70 | Ki-24 antigen | Surface antigen CD70 | CD27 ligand | CD27-L | CD70 antigen | CD70 molecule | TNFSF7
- Recommended Dilution: IHC-P
- 5 - 10 µg/ml
- UniProt Number
- P32970
- NCBI GenBank
- NM_001252 | NP_001243.1
- SwissProt
- P32970
Target
- Target
- CD27L / CD70
- Antigen Species
- Human
- Specificity
- Human CD70. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Epitope
- Human CD70. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Gene Name
- CD70
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Synthetic 17 amino acid peptide from internal region of human CD70. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon, Monkey, Marmoset (94%); Bovine, Rabbit (82%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.1% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Mass Cytometry Analysis Reveals that Specific Intratumoral CD4+<sup> T Cell Subsets Correlate with Patient Survival in Follicular Lymphoma. Yang ZZ, Kim HJ, Villasboas JC, Price-Troska T, Jalali S, Wu H, Luchtel RA, Polley MC, Novak AJ, Ansell SM. Cell reports. 2019 February;26:2178-2193.
PubMed: 30784598 · PMC: PMC6402596
CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity. Tim Sauer, Kathan Parikh, Sandhya Sharma, Bilal Omer, David Sedloev, Qian Chen, Linus Angenendt, Christoph Schliemann, Michael Schmitt, Carsten Müller-Tidow, Stephen Gottschalk, Cliona M Rooney. Blood. 2021 July;138:318-330.
PubMed: 34323938 · PMC: PMC8323977
