LSBio
Polyclonal Rabbit anti-Human HIF3A / HIF3-Alpha Antibody (aa497-514, WB)

WB of HIF3A / HIF3-Alpha antibody. WB: Rat Brain Tissue Lysate.

Polyclonal Rabbit anti-Human HIF3A / HIF3-Alpha Antibody (aa497-514, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Western Blot
Reactivity:Human, Non-Human Primate, Rat
Format:Lyophilized
See all Human HIF3A / HIF3-Alpha antibodies →
$480.00each
Catalog Number: LS-C313254-100

For bulk orders or custom formulations:

Request a Quote

Overview

Description
HIF3-Alpha antibody LS-C313254 is an unconjugated rabbit polyclonal antibody to HIF3-Alpha (HIF3A) (aa497-514) from human. It is reactive with human, rat and monkey. Validated for WB.
Application
WB
Reactivity
Hu, NHP, Rt
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
BHLHe17 | HIF-3A | IPAS | HIF3-alpha-1 | HIF3A | Inhibitory PAS domain protein | PASD7 | HIF-3-alpha | HIF3-alpha | Member of PAS protein 7 | MOP7
UniProt Number
Q9Y2N7
NCBI GenBank
NM_152795, NP_690008.2
SwissProt
Q9Y2N7

Target

Target
Human HIF3A / HIF3-Alpha
Antigen Species
Hu
Epitope
Expressed in vascular cells (at protein level) (PubMed:21069422). Expressed in kidney (PubMed:11573933, PubMed:19694616). Expressed in lung epithelial cells (PubMed:16775626). Expressed in endothelial cells (venous and arterial cells from umbilical cord and aortic endothelial cells) and in vascular smooth muscle cells (aorta) (PubMed:21069422). Strongly expressed in the heart, placenta, and skeletal muscle, whereas a weak expression profile was found in the lung, liver, and kidney (PubMed:12538644). Expressed weakly in cell renal cell carcinoma (CC-RCC) compared to normal renal cells (PubMed:16126907). Expression is down-regulated in numerous kidney tumor cells compared to non tumor kidney tissues (PubMed:16126907). Isoform 2 is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas and in numerous cancer cell lines (PubMed:20416395). Isoform 3 and isoform 4 are weakly expressed in heart, placenta, lung, liver, skeletal muscle and pancreas (PubMed:20416395). Isoform 4 is expressed in fetal tissues, such as heart, brain, thymus, lung, liver, skeletal kidney and spleen (PubMed:20416395). Isoform 3 is weakly expressed in fetal tissues, such as liver and kidney (PubMed:20416395). .
Gene Name
HIF3A

Antibody

Host Species
Rb
Clonality
Polyclonal

Immunogen

Immunogen
A synthetic peptide corresponding to a sequence at the C-Terminus of human HIF3(497-514 aa DDDFQLNASEQLPRAYHR), different from the related rat and mouse sequences by five amino acids.
Immunogen Type
SP-Lin

Format

Conjugate/Label
Unconj
Format
Lyophilized
Formulation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg Thimerosal, 0.05mg sodium azide.
Concentration
0.5 mg/mL
Preservative
Yes
Purification Method
AP

Storage & Handling

Storage Conditions
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Recommended Storage Buffer
NaCl

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.