LSBio
GAP43 Antibody (clone 2G13, Supernatant)

GAP43 Antibody (clone 2G13, Supernatant)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin
Reactivity:Chicken
Format:Liquid
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$519.00each
Catalog Number: LS-C43839-2

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Overview

Description
GAP43 antibody LS-C43839 is an unconjugated mouse monoclonal antibody to chicken GAP43. Validated for IHC.
Application
IHC-F, IHC-P
Reactivity
Ck
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Axonal membrane protein GAP-43 | B-50 | Growth associated protein 43 | Growth-associated protein 43 | Neural phosphoprotein B-50 | Neuromodulin | PP46 | GAP-43 | GAP43 | Protein F1
UniProt Number
P17677
SwissProt
P17677

Target

Target
Chicken GAP43
Antigen Species
Ck
Epitope
Recognizes a protein originally termed 2G13P which is localized to growth cones. Subsequent investigation has identified this protein to be 40S ribosomal protein SA, also known as 37 kD laminin receptor precursor or Laminin receptor 1. 40S ribosomal protein SA is a 296 amino acid ~37kD membrane, cytoplasmic and nuclear protein required for the assembly and/or stability of the 40S ribosomal subunit. In vertebrate evolution the molecule has acquired a secondary function as a laminin receptor. In growth cones expression is notable particularly in filopodia and lamellipodia in developing rat CNS and embryonic neurons in culture. 40S ribosomal protein SA interacts with the filamentous actin cytoskeleton and therefore may be involved in growth cone motility. Has been used for the detection of growth cones by immunohistochemistry and identification of 40S ribosomal protein SA by western blotting in chicken and rat samples.
Gene Name
GAP43

Antibody

Host Species
Ms
Clonality
Monoclonal
Clone
2G13
Isotype
IgM

Immunogen

Immunogen
Embryonic chick tectal membranes.
Immunogen Type
Tiss-Extr

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
0.09% Sodium Azide
Volume
2 Milliliter
Preservative
Yes

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

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