Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with MUC1 Recombinant Rabbit Monoclonal Antibody (MUC1/2729R).
EMA / MUC1 Antibody (clone MUC1/2729R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751282-100
Catalog Number: LS-C751282
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- Description
- MUC1 antibody LS-C751282 is an unconjugated rabbit recombinant monoclonal antibody to human MUC1 (EMA). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CA15-3 | CD227 | Carcinoma-associated mucin | CD227 antigen | DF3 antigen | Episialin | Epithelial membrane antigen | H23 antigen | H23AG | Krebs von den Lungen-6 | MAM6 | MUC1/ZD | MUC-1/SEC | Mucin-1 | Pem | KL-6 | MUC-1/X | MUC1 | Tumor-associated mucin | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | PUM | EMA | MUC-1 | Mucin 1, transmembrane
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P15941
- NCBI GenBank
- NM_002456 | NP_002447.4
- SwissProt
- P15941
Target
- Target
- Human EMA / MUC1
- Antigen Species
- Human
- Epitope
- In Western blotting, it recognizes proteins in MW range of 265-400 kDa , identified as different glycoforms of EMA. This MAb reacts with the DTRP epitope in the tandem repeats. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
- Gene Name
- MUC1
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- MUC1/2729R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human MUC1 protein. Antigen Molecular Weight: 265-400 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS