Formalin-fixed, paraffin-embedded human Lung SqCC stained with EGFRvIII Rabbit Recombinant Monoclonal Antibody (GFR/2600R).

EGFR Antibody (clone GFR/2600R, Azide-free, Carrier-free)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Recombinant Monoclonal
Applications:	Immunohistochemistry (general), Immunohistochemistry, Paraffin, Sodium Dodecyl-Sulfate Polyacrylamide Gel Electrophoresis / Purity Check
Reactivity:	Human
Format:	Liquid

$586.00each

Catalog Number: LS-C751122-100

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Overview

Description: EGFR antibody LS-C751122 is an unconjugated rabbit recombinant monoclonal antibody to human EGFR. Validated for IHC and SDS-PAGE.
Application: IHC, IHC-P, SDS-PAGE
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: EGFR | EGF Receptor | ERBB | ERBB1 | MENA | PIG61 | Proto-oncogene c-ErbB-1 | V-erb-b homolog | EGF-R | HER1
Recommended Dilution: IHC-P: 1 - 2 µg/ml
UniProt Number: P00533
NCBI GenBank: NM_005228 | NP_005219.2
SwissProt: P00533

Target

Target: Human EGFR
Antigen Species: Human
Epitope: EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Gene Name: EGFR

Antibody

Host Species: Rabbit
Clonality: Recombinant Monoclonal
Clone: GFR/2600R
Isotype: IgG
Origin Species: Human

Immunogen

Immunogen: 14 AA peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC) KLH conjugate of EGFRvIII. Antigen Molecular Weight: ~145 kDa (vIII variant)
Immunogen Type: Fusion Protein (e.g., GST, MBP tag)