Formalin-fixed, paraffin-embedded human Pancreas stained with Chromogranin A Mouse Recombinant Monoclonal Antibody (rCHGA/798).
CHGA / Chromogranin A Antibody (clone rCHGA/798)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751096-20
Catalog Number: LS-C751096
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- Description
- Chromogranin A antibody LS-C751096 is an unconjugated mouse recombinant monoclonal antibody to human Chromogranin A (CHGA). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- Chromogranin A | Chromogranin-A | Pancreastatin | Pituitary secretory protein I | Vasostatin I | SP-I | CHGA | Vasostatin II
- Recommended Dilution: IHC-P
- 0.25 - 0.5 µg/ml
- UniProt Number
- P10645
- NCBI GenBank
- NM_001275 | NP_001266.1
- SwissProt
- P10645
Target
- Target
- Human CHGA / Chromogranin A
- Antigen Species
- Human
- Epitope
- Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
- Gene Name
- CHGA
Antibody
- Host Species
- Mouse
- Clonality
- Recombinant Monoclonal
- Clone
- rCHGA/798
- Isotype
- IgG1
- Light Chain
- Kappa Light Chain
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human Chromogranin A (CHGA) protein. Antigen Molecular Weight: 68-75 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS