Formalin-fixed, paraffin-embedded human Pancreas stained with Chromogranin A Rabbit Recombinant Monoclonal Ab (CHGA/1731R).
CHGA / Chromogranin A Antibody (clone CHGA/1731R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751099-100
Catalog Number: LS-C751099
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- Description
- Chromogranin A antibody LS-C751099 is an unconjugated rabbit recombinant monoclonal antibody to human Chromogranin A (CHGA). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Nonreactive Species
- Rat
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- Chromogranin A | Chromogranin-A | Pancreastatin | Pituitary secretory protein I | Vasostatin I | SP-I | CHGA | Vasostatin II
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P10645
- NCBI GenBank
- NM_001275 | NP_001266.1
- SwissProt
- P10645
Target
- Target
- Human CHGA / Chromogranin A
- Antigen Species
- Human
- Epitope
- Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
- Gene Name
- CHGA
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- CHGA/1731R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human Chromogranin A (CHGA) protein. Antigen Molecular Weight: 68-75 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS