Formalin-fixed, paraffin-embedded Human Renal Cell Carcinoma stained with KSP-Cadherin Rabbit Recombinant Monoclonal Antibody (CDH16/1532R)
CDH16 / Cadherin 16 Antibody (clone CDH16/1532R, Azide-free, Carrier-free)
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| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751078-100
Catalog Number: LS-C751078
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- Description
- Cadherin 16 antibody LS-C751078 is an unconjugated rabbit recombinant monoclonal antibody to human Cadherin 16 (CDH16). Validated for Flow, IHC and WB.
- Application
- FC, IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- Cadherin 16, KSP-cadherin | Cadherin 16 | Cadherin-16 | CDH16 | Kidney-specific cadherin | KSP-cadherin
- Recommended Dilution: FC
- 1 - 2 µg/10E6 cells
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- Recommended Dilution: WB
- 1 - 2 µg/ml
- UniProt Number
- O75309
- NCBI GenBank
- NM_004062 | NP_004053.1
- SwissProt
- O75309
Target
- Target
- Human CDH16 / Cadherin 16
- Antigen Species
- Human
- Epitope
- This MAb recognizes a protein of 130 kDa , identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
- Gene Name
- CDH16
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- CDH16/1532R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human CDH16 protein. Antigen Molecular Weight: 130 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS