Formalin-fixed, paraffin-embedded human Tonsil stained with CD79a Rabbit Recombinant Monoclonal Antibody (IGA/1790R).
CD79A / CD79 Alpha Antibody (aa202-216, clone IGA/1790R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Flow Cytometry, Immunofluorescence, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751485-100
Catalog Number: LS-C751485
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- Description
- CD79 Alpha antibody LS-C751485 is an unconjugated rabbit recombinant monoclonal antibody to human CD79 Alpha (CD79A) (aa202-216). Validated for Flow, IF, IHC and WB.
- Application
- FC, IF, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CD79a antigen | CD79A | Ig-alpha | MB-1 | MB-1 membrane glycoprotein | Surface IgM-associated protein | MB1
- Recommended Dilution: FC
- 1 - 2 µg/10E6 cells
- Recommended Dilution: IF/ICC
- 1 - 2 µg/ml
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- Recommended Dilution: WB
- 0.5 - 1 µg/ml
- UniProt Number
- P11912
- NCBI GenBank
- NM_021601 | NP_001774.1
- SwissProt
- P11912
Target
- Target
- Human CD79A / CD79 Alpha
- Antigen Species
- Human
- Epitope
- A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
- Gene Name
- CD79A
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- IGA/1790R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- A synthetic peptide of human CD79a protein. Antigen Molecular Weight: 44 kDa
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS