Formalin-fixed, paraffin-embedded human Angiosarcoma stained with CD34 Recombinant Rabbit Monoclonal Antibody (HPCA1/2598R).

CD34 Antibody (clone HPCA1/2598R, Azide-free, Carrier-free)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Recombinant Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$586.00each

Catalog Number: LS-C751467-100

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Overview

Description: CD34 antibody LS-C751467 is an unconjugated rabbit recombinant monoclonal antibody to human CD34. Validated for Flow and IHC.
Application: FC, IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: CD34 | CD34 molecule | CD34 antigen | HPCA1
Recommended Dilution: FC: 0.5 - 1 µg/10E6 cells
Recommended Dilution: IHC-P: 1 - 2 µg/ml
UniProt Number: P28906
NCBI GenBank: NM_001773 | NP_001764.1
SwissProt: P28906

Target

Target: Human CD34
Antigen Species: Human
Epitope: This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120 kDa , which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity.
Gene Name: CD34