
CD11 + CD18 Antibody (clone 24, FITC)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunocytochemistry, Immunofluorescence |
| Reactivity: | Human |
| Format: | Liquid |
$647.00each
Catalog Number: LS-C827860-50
Catalog Number: LS-C827860
For bulk orders or custom formulations:
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- Description
- CD11 + CD18 antibody LS-C827860 is an FITC-conjugated mouse monoclonal antibody to human CD11 + CD18. Validated for Flow, ICC and IF.
- Application
- FC, ICC, IF
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
Target
- Target
- Human CD11 + CD18
- Antigen Species
- Human
- Epitope
- This antibody recognizes integrin alpha L,M,X/Beta 2 (CD11/CD18). Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits which mediate cell-cell and cell-extracellular matrix attachments. Integrin beta2 (CD18) associates with integrin alpha L (CD11a) to form the leukocyte function-associated antigen-1 (LFA-1) with integrin alpha M (CD11b) to form Complement Receptor 3 (CR3) and with integrin alpha X (CD11c) to form Complement Receptor 4 (CR4). Each integrin receptor can bind various Intercellular adhesion molecules (ICAMs). Aberrant integrin expression has been found in many epithelial tumors. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 24
- Isotype
- IgG1
Immunogen
- Immunogen
- Fibronectin-purified human monocytes.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Fluorescein Isothiocyanate
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 0.9 mg/mL
- Volume
- 50 Microliter
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
