Formalin-fixed, paraffin-embedded human Leiomyosarcoma stained with Caldesmon Mouse Recombinant Monoclonal Antibody (rCALD1/820).
CALD1 / Caldesmon Antibody (clone rCALD1/820, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Sodium Dodecyl-Sulfate Polyacrylamide Gel Electrophoresis / Purity Check |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751426-100
Catalog Number: LS-C751426
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- Description
- Caldesmon antibody LS-C751426 is an unconjugated mouse recombinant monoclonal antibody to human Caldesmon (CALD1). Validated for IHC and SDS-PAGE.
- Application
- IHC, SDS-PAGE
- Reactivity
- Hu
- Nonreactive Species
- Rat
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CALD1 | Caldesmon | Caldesmon 1 | HCAD | LCAD | H-CAD | NAG22 | CDM | L-CAD
- Recommended Dilution: IHC-P
- 0.25-0.5 ug/ml
- UniProt Number
- Q05682
- NCBI GenBank
- NM_004342 | NP_004333.1
- SwissProt
- Q05682
Target
- Target
- Human CALD1 / Caldesmon
- Antigen Species
- Human
- Epitope
- Recognizes a protein of 150 kDa , which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa ) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa ) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
- Gene Name
- CALD1
Antibody
- Host Species
- Mouse
- Clonality
- Recombinant Monoclonal
- Clone
- rCALD1/820
- Isotype
- IgG1
- Light Chain
- Kappa Light Chain
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human CALD1 protein. Antigen Molecular Weight: 150 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS