LSBio
Polyclonal Rabbit anti-Human BCL2 / Bcl-2 Antibody (Biotin)

Polyclonal Rabbit anti-Human BCL2 / Bcl-2 Antibody (Biotin)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay
Reactivity:Human
Format:Liquid
See all Human BCL2 / Bcl-2 antibodies →
$300.00each
Catalog Number: LS-C500254-50

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Overview

Description
Bcl-2 antibody LS-C500254 is a biotin-conjugated rabbit polyclonal antibody to human Bcl-2 (BCL2). Validated for ELISA.
Application
ELISA
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Apoptosis regulator Bcl-2 | BCL2 | B-cell CLL/lymphoma 2 | B-cell lymphoma protein 2 | Bcl-2 | PPP1R50
UniProt Number
P10415
NCBI GenBank
NM_000633, NP_000624.2
SwissProt
P10415

Target

Target
Human BCL2 / Bcl-2
Antigen Species
Hu
Epitope
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Gene Name
BCL2

Antibody

Host Species
Rb
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Apoptosis regulator Bcl-2 protein (31-80AA)
Immunogen Type
Recom

Format

Conjugate/Label
Biotin
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Prot G

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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