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Recombinant Monoclonal Rabbit anti-Human BCL10 / BCL-10 Antibody (clone BL10/2988R, aa122-168, IHC, IF)

Formalin-fixed, paraffin-embedded human Tonsil stained with BCL10 Recombinant Rabbit Monoclonal Antibody (BL10/2988R).

Recombinant Monoclonal Rabbit anti-Human BCL10 / BCL-10 Antibody (clone BL10/2988R, aa122-168, IHC, IF)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Flow Cytometry, Immunofluorescence, Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Human BCL10 / BCL-10 antibodies →
$379.00each
Catalog Number: LS-C751433-20

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Overview

Description
BCL-10 antibody LS-C751433 is an unconjugated rabbit recombinant monoclonal antibody to human BCL-10 (BCL10) (aa122-168). Validated for Flow, IF and IHC.
Application
FC, IF, IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
BCL10 | Bcl-10 | B-cell CLL/lymphoma 10 | B-cell lymphoma/leukemia 10 | CARMEN | CARD-like apoptotic protein | CCARMEN | C-E10 | CIPER | Cellular-E10 | HCLAP | Cellular homolog of vCARMEN | CLAP | ME10
UniProt Number
O95999
SwissProt
O95999
Recommended Dilution
ApplicationDilution
FC0.5 - 1 µg/10E6 cells
IF/ICC1 - 2 µg/ml
IHC-P0.5 - 1 µg/ml

Target

Target
Human BCL10 / BCL-10
Antigen Species
Human
Epitope
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF-kappa-B activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Gene Name
BCL10

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
BL10/2988R
Isotype
IgG
Origin Species
Human

Immunogen

Immunogen
Recombinant human BCL10 protein fragment (around aa122-168). Antigen Molecular Weight: 33 kDa
Immunogen Type
Recombinant Protein Fragment

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.