Formalin-fixed, paraffin-embedded human Tonsil stained with BCL10 Recombinant Rabbit Monoclonal Antibody (BL10/2988R).
BCL10 / BCL-10 Antibody (aa122-168, clone BL10/2988R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Flow Cytometry, Immunofluorescence, Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751432-100
Catalog Number: LS-C751432
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- Description
- BCL-10 antibody LS-C751432 is an unconjugated rabbit recombinant monoclonal antibody to human BCL-10 (BCL10) (aa122-168). Validated for Flow, IF and IHC.
- Application
- FC, IF, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- BCL10 | Bcl-10 | B-cell CLL/lymphoma 10 | B-cell lymphoma/leukemia 10 | CARMEN | CARD-like apoptotic protein | CCARMEN | C-E10 | CIPER | Cellular-E10 | HCLAP | Cellular homolog of vCARMEN | CLAP | ME10
- UniProt Number
- O95999
- NCBI GenBank
- NM_003921 | NP_003912.1
- SwissProt
- O95999
Recommended Dilution
| Application | Dilution |
|---|---|
| FC | 0.5 - 1 µg/10E6 cells |
| IF/ICC | 1 - 2 µg/ml |
| IHC-P | 0.5 - 1 µg/ml |
Target
- Target
- Human BCL10 / BCL-10
- Antigen Species
- Human
- Epitope
- BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF-kappa-B activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
- Gene Name
- BCL10
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- BL10/2988R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant human BCL10 protein fragment (around aa122-168). Antigen Molecular Weight: 33 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS