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Anti-CYP11B2 / Aldosterone Synthase Antibody (aa175-192) LS-C6353

Ordering

Wt. Vol. Conc. Price
- 500 µl - $515
Inquire for larger quantities

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Most Popular CYP11B2 / Aldosterone Synthase Antibodies

Anti-CYP11B2 / Aldosterone Synthase Antibody (aa175-192) LS-C6353
Mouse Monoclonal (IgG1,k) to Rat CYP11B2 / Aldosterone Synthase
Rat
IHC - Paraffin, ICC, Western blot, ELISA
Unconjugated
Anti-CYP11B2 / Aldosterone Synthase Antibody (C-Terminus) LS-C107630
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
Western blot
Unconjugated
Western blot Image
Anti-CYP11B2 / Aldosterone Synthase Antibody (aa120-147, Azide-free, HRP) LS-C208751
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
HRP Conjugated, Azide-free

100% Guaranteed 100% Guaranteed Publications Publications (1)
Mouse Monoclonal (IgG1,k) to Rat CYP11B2 / Aldosterone Synthase
Rat
IHC - Paraffin, ICC, Western blot, ELISA
Unconjugated

Details

Rat CYP11B2 / Aldosterone Synthase
Mouse
Rat (tested or 100% immunogen sequence identity)
Mouse, Hamster (at least 90% immunogen sequence identity)
IgG1,k Monoclonal
Unconjugated
Tissue culture supernatant
Unmodified

Applications

  • IHC - Paraffin
  • ICC
  • Western blot
  • ELISA

Specificity and Use

CYP11B2 / Aldosterone Synthase antibody was raised against rat Aldo-1-MAP aa175-192 (KVRQNARGSLTMDVQQSL-MAP). Percent identity by BLAST analysis: Rat (100%); Mouse, Hamster (94%); Gorilla (83%).
aa175-192
Recognizes rat cytochrome p450 aldosterone synthase. Species cross-reactivity: Mouse.
Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA. Immunohistochemistry: STF on paraffin embedded tissue. Requires Microwave or pressure cooker antigen retrieval. Recommended counter stain is Gill's Hematoxylin.

Packaging

PBS, 0.09% sodium azide, 50% glycerol.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

Publications (1)

1
Transgenic GATA-4 expression induces adrenocortical tumorigenesis in C57Bl/6 mice. Chrusciel M, Vuorenoja S, Mohanty B, Rivero-M[Character fc]ller A, Li X, Toppari J, Huhtaniemi I, Rahman NA. Journal of cell science. 2013 Apr;126:1845-57. [Full Text Article] [PubMed:23444372] [PMC:PMC3678410]

About CYP11B2 / Aldosterone Synthase

P19099 NM_000498 NP_000489.3

CYP11B2 Antibody, ALDOS Antibody, Aldosterone synthase Antibody, CYP11BL Antibody, CYPXIB2 Antibody, Cytochrome P-450Aldo Antibody, Cytochrome P-450C18 Antibody, P-450C18 Antibody, p450aldo Antibody, Steroid 18-hydroxylase Antibody, Steroid 11-beta-monooxygenase Antibody, CYP11B Antibody, p450C18 Antibody, Steroid 11-beta/18-hydroxylase Antibody

CYP11B2 / Aldosterone Synthase is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity.

Requested From: United States
Date Requested: 12/4/2016

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