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Anti-CTDSP2 Antibody (aa12-42) LS-C101053

Catalog	Size	Price
LS-C101053-400	400 µl	Unavailable

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35 CTDSP2 Antibodies

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Anti-CTDSP2 Antibody (C-Terminus) LS-C63950

Antibody:	Mouse Monoclonal (IgG2b) to Human CTDSP2
Reactivity:	Human
Application:	Western blot
Format:	Unconjugated

Anti-CTDSP2 Antibody (aa12-42) LS-C101053

Antibody:	Rabbit Polyclonal to Human CTDSP2
Reactivity:	Human, Mouse
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-CTDSP2 Antibody LS-C307118

Antibody:	Mouse Monoclonal (IgG2a,k) to Human CTDSP2
Reactivity:	Human
Application:	Western blot, ELISA
Format:	Unconjugated

Anti-CTDSP2 Antibody (aa10-39) LS-C320659

Antibody:	Rabbit Polyclonal (IgG) to Human CTDSP2
Reactivity:	Human
Application:	Western blot, ELISA
Format:	Unconjugated

Anti-CTDSP2 Antibody (C-Terminus) IHC-plus™ LS-B11519

Antibody:	Rabbit Polyclonal to Human CTDSP2
Reactivity:	Human, Monkey, Mouse, Bat, Bovine, Horse, Pig
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Antibody:	Rabbit Polyclonal to Human CTDSP2
Reactivity:	Human, Mouse
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Details

Target:	Human CTDSP2
Host:	Rabbit
Reactivity:	Human, Mouse (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Ammonium sulfate precipitation
Modifications:	Unmodified

Applications

Approved:

IHC - Paraffin (1:50 - 1:100)
Western blot (1:1000)

Specificity and Use

Blocking Peptide:

LS-E9592 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C101053. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

aa12-42

Specificity:

This CTDSP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-42 amino acids from the N-terminal region of human CTDSP2.

Packaging

Presentation:	PBS, 0.09% sodium azide
Storage:	Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions:	For research use only.

About CTDSP2

Uniprot: O14595 NCBI: NM_005730 NP_005721.3

Synonyms: CTDSP2 Antibody, NLI-interacting factor 2 Antibody, OS4 Antibody, PSR2 Antibody, Small CTD phosphatase 2 Antibody, NIF2 Antibody, Protein OS-4 Antibody

Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

(More About CTDSP2)

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Technical Help Review

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Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Immunohistochemistry

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CTDSP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

Western blot of anti-CTDSP2 Antibody in mouse lung tissue lysates (35 ug/lane). CTDSP2(arrow) was detected using the purified antibody.

Western blot

Western blot of anti-CTDSP2 Antibody in HepG2 cell line lysates (35 ug/lane). hCTDSP2-S27(arrow) was detected using the purified antibody.

Requested From:
Date Requested: 8/23/2017

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