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Anti-CLDN12 / Claudin 12 Antibody (N-Terminus) IHC-plus™ LS-B2181

Note: This antibody replaces LS-C6167


Wt. Vol. Conc. Price
50 µg - 0.25 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular CLDN12 / Claudin 12 Antibodies

Anti-CLDN12 / Claudin 12 Antibody (N-Terminus) IHC-plus™ LS-B2181
Rabbit Polyclonal (IgG) to Human CLDN12 / Claudin 12
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot
Immunohistochemistry Image
Anti-CLDN12 / Claudin 12 Antibody (aa19-46) LS-C168808
Rabbit Polyclonal to Human CLDN12 / Claudin 12
Western blot, Flow Cytometry
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human CLDN12 / Claudin 12
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot


Human CLDN12 / Claudin 12
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (5 µg/ml)
  • Western blot (1 - 3 µg/ml)

Specificity and Use

CLDN12 / Claudin 12 antibody was raised against synthetic peptide derived from the N-terminal region of mouse and human Claudin 12.
Recognizes mouse Claudin 12 protein at ~27kD in Western blots. Cross-reactivity has been confirmed on mouse lung, colon and kidney homogenates. Recognizes human protein in IHC-P.
Immunohistochemistry: LS-B2181 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2181 was determined to be 5 ug/ml. Immunofluorescence: 5 ug/ml, performed using ethanol-fixed mouse colon. Positive control: Mouse lung, colon, and kidney homogenates.


PBS, pH 7.4, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About CLDN12 / Claudin 12

P56749 NM_012129 NP_036261.1

CLDN12 Antibody, Claudin 12 Antibody, Claudin-12 Antibody

CLDN12 / Claudin 12 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.


Anti-CLDN12 / Claudin 12 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2181 concentration 5 ug/ml.

Requested From: United States
Date Requested: 10/21/2016

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