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Anti-CBLC Antibody (aa424-453) LS-C98810

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CBLC Antibodies

Anti-CBLC Antibody (aa444-458) IHC-plus™ LS-B208
Rabbit Polyclonal to Human CBLC
Human
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CBLC Antibody (C-Terminus, APC) LS-C275729
Rabbit Polyclonal (IgG) to Human CBLC
Human
IHC, Western blot, ELISA
APC Conjugated
Anti-CBLC Antibody LS-C482888
Rabbit Polyclonal to Human CBLC
Human
ICC, Immunofluorescence, Western blot
Unconjugated
Immunofluorescence Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human CBLC
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human CBLC
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

CBLC antibody was raised against kLH-conjugated synthetic peptide between amino acids 424-453 from C-terminal region of human CBLC.
LS-E1787 - Lyophilized - 100 µg - $145.00
aa424-453

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About CBLC

Q9ULV8 NM_012116 NP_036248.3

CBLC Antibody, CBL-3 Antibody, CBL3 Antibody, RNF57 Antibody, SH3-binding protein CBL-C Antibody, SH3-binding protein CBL-3 Antibody, CBL-c Antibody, CBL-SL Antibody, RING finger protein 57 Antibody

Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Functionally coupled with the E2 ubiquitin-protein ligases UB2D1, UB2D2 and UB2D3. Regulator of EGFR mediated signal transduction; upon EGF activation, ubiquitinates EGFR. Isoform 1, but not isoform 2, inhibits EGF stimulated MAPK1 activation. Promotes ubiquitination of SRC phosphorylated at 'Tyr-419'.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
CBLC Antibody (R439) western blot of K562 cell line lysates (35 ug/lane). The CBLC antibody detected the CBLC protein (arrow).

Requested From: United States
Date Requested: 12/5/2016

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