Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CA3 Antibody, Carbonate dehydratase III Antibody, Carbonic anhydrase 3 Antibody, Carbonic anhydrase III Antibody, CA-III Antibody, CAIII Antibody, Car3 Antibody
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle.
Anti-CA3 / Carbonic Anhydrase III antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5379 concentration 5 ug/ml.
Western blot of CA3 expression in K-562 by CA3 monoclonal antibody (M02), clone 4A12-1A3.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged CA3 is approximately 1 ng/ml as a capture antibody.
Requested From: United States
Date Requested: 10/24/2016