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Anti-BIRC1 / NAIP Antibody (C-Terminus) IHC-plus™ LS-B455

Note: This antibody replaces LS-C433

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular BIRC1 / NAIP Antibodies

Anti-BIRC1 / NAIP Antibody (C-Terminus) IHC-plus™ LS-B455
Rabbit Polyclonal to Human BIRC1 / NAIP
Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-BIRC1 / NAIP Antibody (aa500-759) LS-C295587
Rabbit Polyclonal (IgG) to Mouse BIRC1 / NAIP
Mouse
Western blot, ELISA
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human BIRC1 / NAIP
Human
IHC - Paraffin, ICC, Western blot
Unconjugated

Details

Human BIRC1 / NAIP
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ICC
  • Western blot (0.5 - 1 µg/ml)

Specificity and Use

BIRC1 / NAIP antibody was raised against synthetic peptide from human NAIP.
LS-E30068 - Liquid - 50 µg - $145.00
C-Terminus
synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP
Immunohistochemistry: LS-B455 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B455 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

Publications (1)

1
Apoptosis inhibition or inflammation: the role of NAIP protein expression in Hodgkin and non-Hodgkin lymphomas compared to non-neoplastic lymph node. Mazrouei S, Ziaei A, Tanhaee AP, Keyhanian K, Esmaeili M, Baradaran A, Salehi M. PloS one. 2014 9:4. [Full Text Article] [PubMed:22357131] [PMC:PMC3297494]

About BIRC1 / NAIP

Q13075 NM_004536 NP_004527.2

NAIP Antibody, PsiNAIP Antibody, BIRC1 Antibody, NLRB1 Antibody

Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor-neuron apoptosis induced by a variety of signals.

Immunohistochemistry

Immunohistochemistry
Anti-NAIP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B455 concentration 5 ug/ml.

Immunocytochemistry

Immunocytochemistry
Immunocytochemistry of NAIP in A549 cells with NAIP antibody at 10 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of NAIP in A549 cells with NAIP antibody at 20 ug/ml.

Western blot

Western blot
Western blot of NAIP in PC-3 cell lysate with NAIP antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.

Requested From: United States
Date Requested: 12/4/2016

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