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Anti-ASIP Antibody (N-Terminus) LS-C34916


Wt. Vol. Conc. Price
- 50 µl - $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

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Rabbit Polyclonal (IgG) to Mouse ASIP
Western blot, ELISA


Mouse ASIP
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal


  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:50000)

Specificity and Use

ASIP antibody was raised against synthetic peptide consisting of 21aa near the N-terminus of mouse Agouti (KLH coupled).
Recognizes mouse Agouti. No homology is seen with AGRP, tubby, tub, TULP1 and TULP2. Species sequence Homology: Human: 80% (16/20aa); porcine: 73% (14/19aa); fox: 75% (15/20); bovine: 60% (12/20aa) agouti proteins.
Suitable for use in Western Blot, ELISA. Western Blot: 1:1000-1:5000 (ECL). ELISA: 1:10000-1:50000 using 50-100 ng control peptide per well.


Antibody in PBS, 0.05% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About ASIP

P42127 NM_001672 NP_001663.2

ASIP Antibody, Agouti-signaling protein Antibody, AGTIL Antibody, Agouti signaling protein Antibody, AGTI Antibody, Agouti switch protein Antibody, AGSW Antibody, SHEP9 Antibody, ASP Antibody, Nonagouti homolog Antibody

Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action.

Requested From: United States
Date Requested: 10/27/2016

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