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Anti-ANAPC11 / APC11 Antibody (C-Terminus) LS-C19022


Wt. Vol. Conc. Price
- 100 µl - $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular ANAPC11 / APC11 Antibodies

Anti-ANAPC11 / APC11 Antibody (Internal) IHC-plus™ LS-B6980
Rabbit Polyclonal to Human ANAPC11 / APC11
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (2)
Rabbit Polyclonal to Human ANAPC11 / APC11
Western blot, Immunoprecipitation, ELISA


Human ANAPC11 / APC11
Human (tested or 100% immunogen sequence identity)
Delipidated and defibrinated


  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation
  • ELISA (1:2000 - 1:10000)

Specificity and Use

ANAPC11 / APC11 antibody was raised against synthetic peptide from human ANAPC11 / APC11.
Amino acids 76-84 of Human APC11 (C-terminal) coupled to KLH.
This antibody reacts with human APC11 by western blot and immunoprecipitation. The antibody immunoprecipitates in vitro translated protein and protein from overexpressing cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of related proteins (APC2) does occur. A 9.8 kD band corresponding to human APC11 is detected. Most cell lines or tissues expressing APC11 can be used as a positive control. Researchers should determine optimal titers for other applications.


0.01% sodium azide.
Store vial at -20 C prior to opening. Aliquot contents and freeze at -20 C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
For research use only.

Publications (2)

Association with cullin partners protects ROC proteins from proteasome-dependent degradation. Ohta T, Michel JJ, Xiong Y. Oncogene. 1999 18:6758-66. [PubMed:10597284]
Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. Furukawa M, Ohta T, Xiong Y. The Journal of biological chemistry. 2002 277:15758-65. [PubMed:11861641]

About ANAPC11 / APC11

Q9NYG5 NM_016476 NP_057560.8

ANAPC11 Antibody, Apc11p Antibody, APC11 Antibody, Cyclosome subunit 11 Antibody, HSPC214 Antibody

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Requested From: United States
Date Requested: 10/28/2016

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