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Anti-ALOX5 / 5-LOX Antibody (phospho-Ser523) LS-C178

Note: This antibody replaces LS-C71727, LS-C56974, LS-C49272

Ordering

Wt. Vol. Conc. Price
- 100 µl - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ALOX5 / 5-LOX Antibodies

Anti-ALOX5 / 5-LOX Antibody (aa130-149) IHC-plus™ LS-B1499
Rabbit Polyclonal (IgG) to Human ALOX5 / 5-LOX
Human, Rat, Bovine
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-ALOX5 / 5-LOX Antibody (aa100-200) IHC-plus™ LS-B2144
Rabbit Polyclonal to Human ALOX5 / 5-LOX
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-ALOX5 / 5-LOX Antibody (aa600-674) IHC-plus™ LS-B2164
Rabbit Polyclonal to Human ALOX5 / 5-LOX
Human, Mouse, Rat, Bovine, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human ALOX5 / 5-LOX
Human, Rat
Western blot
Unconjugated

Details

Human ALOX5 / 5-LOX
Rabbit
Human, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

ALOX5 / 5-LOX antibody was raised against phosphopeptide corresponding to amino acid residues surrounding the phosphoSer523 of human 5-lipoxygenase.
pSer523
Specific for the ~80k 5-LO phosphorylated at Ser523 in Western blots

Packaging

50 uL of 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol.
Long term: -20°C; Short term: -20°C
For research use only.

About ALOX5 / 5-LOX

P09917 NM_000698 NP_000689.1

ALOX5 Antibody, 5-lipoxygenase Antibody, 5LPG Antibody, 5-LO Antibody, 5-LOX Antibody, Arachidonate 5-lipoxygenase Antibody, LOG5 Antibody, LOX-5 Antibody, Leukotriene A4 synthase Antibody

ALOX5 / 5-LOX is a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4).

Western blot

Western blot
Western blot of rat cortex lysate showing specific immunolabeling of the ~80k doublet of 5-LO phosphorylated at Ser523 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda-phosphatase). The blot is ide

Western blot

Western blot
Western blot of rat cortex lysate showing specific immunolabeling of the ~80k doublet of 5-LO phosphorylated at Ser523 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: l-Ptase). The blot is identical to the control except that it was incubated in l-Ptase (1200 units for 30 min) before being exposed to the Anti-Ser523 5-LO. The immunolabeling is completely eliminated by treatment with l-Ptase.

Requested From: United States
Date Requested: 12/9/2016

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