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Anti-Acrosin Antibody (clone ACR-2) LS-C45883


Wt. Vol. Conc. Price
100 µg - - Unavailable

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Mouse Monoclonal [clone ACR-2] (IgG1) to Pig Acrosin
ICC, Western blot, Flow Cytometry


Pig Acrosin
Pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [ACR-2]
Protein A purified


  • ICC
  • Western blot
  • Flow Cytometry

Specificity and Use

Acrosin antibody was raised against acid extracts of boar spermatozoa were subjected to hydrophobic chromatography and the pooled fraction with reactivity to N-alpha benzoyl arginine-4-nitroanilide was used for immunization.
Reacts with various forms of porcine acrosin (55, 53, 45 and 35 kD), a typical serine proteinase with trypsin-like specificity. Acrosin is stored in the acrosome of undamaged spermatozoa.
Flow Cytometry: described in Ded et al., 2010. Immunocytochemistry: Application note - Membrane permeabilization (acetone) is essential.


PBS, 15 mM sodium azide, approx., pH 7.4.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About Acrosin

P10323 NM_001097 NP_001088.2

ACR Antibody, ACRS Antibody, Acrosin Antibody, Proacrosin Antibody, Preproacrosin Antibody

Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis.

Requested From: 
Date Requested: 4/24/2017

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