
Formalin-fixed, paraffin-embedded Human Tonsil stained with AIF1 / Iba1 Mouse Recombinant Monoclonal Antibody (rAIF1/1909).
AIF1 / IBA1 Antibody (aa 1-146, clone rAIF1/1909)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751126-20
Catalog Number: LS-C751126
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- Description
- IBA1 antibody LS-C751126 is an unconjugated mouse recombinant monoclonal antibody to human IBA1 (AIF1) (aa 1-146). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- RUO
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- AIF-1 | AIF1 | Em:AF129756.17 | G1 | IRT-1 | Protein G1 | IBA1 | IRT1
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- UniProt Number
- P55008
- NCBI GenBank
- NM_004847, NP_004838.1
- SwissProt
- P55008
Target
- Target
- Human AIF1 / IBA1
- Antigen Species
- Hu
- Epitope
- AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
- Gene Name
- AIF1
Antibody
- Host Species
- Ms
- Clonality
- Recombinant Monoclonal
- Clone
- rAIF1/1909
- Isotype
- IgG1
- Origin Species
- Hu
Immunogen
- Immunogen
- Purified recombinant human AIF1 protein (around aa 1-146). Antigen Molecular Weight: 17 kDa
- Immunogen Type
- Frag-RP
Format
- Conjugate/Label
- Unconj
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Prot A/G
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS
