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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LECT1 / Chondromodulin-I

leukocyte cell derived chemotaxin 1

LECT1 / Chondromodulin-I is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: leukocyte cell derived chemotaxin 1
Synonyms: LECT1, BRICHOS domain containing 3, CHM-I, CHMI, Chondromodulin I, Chondromodulin-I, Chondromodulin-1, MYETS1, BRICD3, CHM1, Chondromodulin
Target Sequences: NM_007015 NP_008946.1 O75829

Publications (1)

1
TGF-ß mediates early angiogenesis and latent fibrosis in an Emilin1-deficient mouse model of aortic valve disease. Munjal C, Opoka AM, Osinska H, James JF, Bressan GM, Hinton RB. Disease models & mechanisms. 2014 7:987-96. (IHC; Mouse) [Full Text Article] [PubMed:25056700] [PMC:PMC4107327] Related Antibodies: LS-C80668.

Viewing 1-25 of 30 items
LECT1 / Chondromodulin-I Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal to Human LECT1 / Chondromodulin-I
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
LECT1 / Chondromodulin-I Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
(1) Publication(s)
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Mouse, Bovine, Rat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
LECT1 / Chondromodulin-I Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Mouse, Bovine, Rat, Human, Monkey
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
LECT1 / Chondromodulin-I Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Mouse, Bovine, Rat, Human, Monkey
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
LECT1 / Chondromodulin-I Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 10-20%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Mouse, Bovine, Rat, Human, Monkey
WB
FITC Conjugated
100µl   1mg/ml   $385.00
LECT1 / Chondromodulin-I Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LECT1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Rabbit Polyclonal to Human LECT1 / Chondromodulin-I
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
LECT1 / Chondromodulin-I Antibody
Select
Rabbit Polyclonal to Human LECT1 / Chondromodulin-I
Human
ICC, IF, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00
LECT1 / Chondromodulin-I Antibody - Immunohistochemistry of paraffin-embedded human heart tissue at dilution 1:100
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Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
ELISA, IHC, IHC-P
Unconjugated
50µl   $235.00; 100µl   $285.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Mouse, Human
IF, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal to Human LECT1 / Chondromodulin-I
Human
IF, WB
Unconjugated
100µl   $385.00
Select
Rabbit Polyclonal to Human LECT1 / Chondromodulin-I
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
IP, WB
Unconjugated
100µl   $605.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
ELISA
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
ELISA
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
ELISA
FITC Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
WB
Unconjugated
100µg   $605.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
WB
HRP Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
WB
Biotin Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
WB
FITC Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
WB
AP Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
WB
APC Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human LECT1 / Chondromodulin-I
Human
WB
PE Conjugated
100µl   $755.00
LECT1 / Chondromodulin-I Antibody - Western blot of recombinant LECT1 / Chondromodulin-I.
Select
Rabbit Polyclonal to Human LECT1 / Chondromodulin-I
Mouse, Human
WB
APC, Cy7 Conjugated
100µl   0.1mg/ml   $385.00; 200µl   0.1mg/ml   $475.00; 1ml   0.1mg/ml   $1,170.00
LECT1 / Chondromodulin-I Antibody - Western blot of recombinant LECT1 / Chondromodulin-I.
Select
Rabbit Polyclonal to Human LECT1 / Chondromodulin-I
Mouse, Human
WB
Cy3 Conjugated
100µl   0.1mg/ml   $355.00; 200µl   0.1mg/ml   $445.00; 1ml   0.1mg/ml   $1,050.00

Viewing 1-25 of 30 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).