Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
LifeSpan provides high-quality, confidential, protein localization data through its immunohistochemistry services. Reseachers can outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies. All studies are conducted under R&D conditions, are confidential, and the results are proprietary to the customer.
All custom protein expression-profiling studies are confidential, are performed on a fee-for-service basis without royalties or milestone payments, and include the following:
Full-Text Reporting: With Full-Text Reporting, LifeSpan's pathologists describe the immunolocalization patterns in detail and provide 3-5 representative images for each tissue sample. This format is useful for studies that require detailed observations and interpretation, such as studies involving CNS tissues, co-localization studies, or those that may involve rare events and minor cell types. Information about each patient sample is also provided.
Full text report on Cardiovascular Disease
Full text report on Neurodegenerative Disease
Full text report with Double-labeling
Full text report on Cancer Tissues
Full text report on Inflammatory Disease
Tabular Reporting with and without Imaging: With Tabular Reporting, LifeSpan's pathologists quantify the signal present in major cell types within each tissue sample using a 0-4 scale and present the results in a table. This format is useful for studies at the initial stages of target characterization, screening studies, or those involving major cell types or in homogeneous tissues. Customers can choose to include selected images for each tissue sample.
Tabular report on Cancer Tissues