SORT1 / Sortilin

sortilin 1

Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

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Products

Antibodies (35)

ELISA Kits (8)

Proteins (6)

Type

Custom (1)

Primary (35)

Recombinant (6)

Sandwich (7)

Target

SORT1 / Sortilin (49)

Reactivity

Human (33)

Mouse (13)

Rat (16)

Pig (8)

Application

IHC (12)

IHC-P (3)

WB (23)

ELISA (11)

IP (1)

Peptide-ELISA (1)

Host

rabbit (31)

mouse (3)

sheep (1)

Product Group

PathPlus Neuro (1)

Isotype

IgG (20)

IgG1 (2)

IgG2a,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (32)

Clone

1B3 (1)

OTI3H4 (2)

Format

96-Well Microplate (3)

96-Well Strip Plate (5)

APC (1)

APC Conjugated (1)

Biotin Conjugated (3)

Carrier-free (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Preservative Free (1)

Unconjugated (22)

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Epitope

aa50-320 (8)

N-Terminus (4)

aa610-754 (4)

Extracellular Domain (2)

aa34-300 (2)

Cytoplasmic Domain (1)

Publications

No (48)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (3)

Plasma (4)

Serum (4)

Tissue Homogenates (3)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-GST (1)

His-SUMO (1)

Species

Human (2)

Mouse (1)

Rat (3)

Source

293F Cells (1)

E. coli (3)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (2)

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SORT1 / Sortilin Antibody (Cytoplasmic Domain) LS-C94912

(4.0) Rating

(1) Publication(s)

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

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Human SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F21281

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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SORT1 / Sortilin Antibody (N-Terminus) LS-C37628

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$832

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SORT1 / Sortilin Antibody (Extracellular Domain) LS-C37627

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$884

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SORT1 / Sortilin Antibody LS-C403604

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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SORT1 / Sortilin Antibody (clone 1B3) LS-C198140

Antibody:

SORT1 / Sortilin Mouse anti-Human Monoclonal (1B3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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Mouse SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F25393

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$854

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SORT1 / Sortilin Antibody LS-C409473

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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SORT1 / Sortilin Antibody (aa50-320) LS-C373041

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal (aa50-320) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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SORT1 / Sortilin Antibody (aa50-320, APC) LS-C718092

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal (aa50-320) (APC) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• APC

• Unconjugated
• APC

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SORT1 / Sortilin Antibody LS-C660394

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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Human SORT1 / Sortilin Protein (Recombinant His-GST) (aa50-320) - LS-G25158

Source:

E. coli

Tag:

His-GST

Molecular Weight:

59.7 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Human SORT1 / Sortilin (Sandwich ELISA) ELISA Kit - LS-F6828

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

Select

PathPlus™ SORT1 / Sortilin Antibody LS-B16484

Neuroscience

(5.0) Rating

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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SORT1 / Sortilin Antibody (N-Terminus) LS-C94806

Antibody:

SORT1 / Sortilin Rabbit anti-Rat Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

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SORT1 / Sortilin Antibody LS-C668404

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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SORT1 / Sortilin Antibody (N-Terminus) LS-C94842

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

Select

SORT1 / Sortilin Antibody LS-C770817

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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SORT1 / Sortilin Antibody LS-C406840

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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SORT1 / Sortilin Antibody LS-C779287

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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SORT1 / Sortilin Antibody LS-C803156

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SORT1 / Sortilin Antibody (N-Terminus) LS-C94818

Antibody:

SORT1 / Sortilin Sheep anti-Rat Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

Select

SORT1 / Sortilin Antibody (Extracellular Domain) LS-C73437

Antibody:

SORT1 / Sortilin Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µl/$688

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SORT1 / Sortilin Antibody (aa34-300, clone OTI3H4) LS-C796519

Antibody:

SORT1 / Sortilin Mouse anti-Human Monoclonal (aa34-300) (OTI3H4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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SORT1 / Sortilin Antibody (aa34-300, clone OTI3H4, Carrier-free) LS-C793191

Antibody:

SORT1 / Sortilin Mouse anti-Human Monoclonal (aa34-300) (Carrier-free) (OTI3H4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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