ITM2C

integral membrane protein 2C

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

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Products

Antibodies (17)

Proteins (8)

Type

Over-Expression Lysate (6)

Primary (17)

Recombinant (2)

Target

ITM2C (25)

Reactivity

Human (17)

Mouse (4)

Rat (4)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (3)

Sheep (3)

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Application

IHC (3)

WB (16)

ELISA (9)

IF (1)

Host

rabbit (15)

mouse (2)

Isotype

IgG (10)

IgG2a (1)

Clonality

monoclonal mc (1)

polyclonal pc (16)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (9)

Epitope

aa27-55 (7)

aa101-150 (4)

aa92-227 (1)

Publications

No (25)

Tag

GST, N-terminus + His, C-terminus (1)

Myc-DDK (Flag) (7)

Species

Human (5)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (4)

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ITM2C Antibody (aa27-55) LS-C322306

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa27-55) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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ITM2C Antibody (aa27-55, Biotin) LS-C260559

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa27-55) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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ITM2C Antibody (aa27-55, FITC) LS-C260560

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa27-55) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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ITM2C Antibody (aa27-55, APC) LS-C260558

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa27-55) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

ITM2C Antibody (aa27-55, Azide-free, HRP) LS-C260561

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa27-55) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

ITM2C Antibody (aa27-55, PE) LS-C260562

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa27-55) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

ITM2C Antibody LS-C666514

Antibody:

ITM2C Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$361

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ITM2C Antibody LS-C666512

Antibody:

ITM2C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

ITM2C Antibody (aa92-227) LS-C178890

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa92-227) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µl/$332

Select

ITM2C Antibody LS-C410449

Antibody:

ITM2C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

ITM2C Antibody LS-C747766

Antibody:

ITM2C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

ITM2C Antibody (aa101-150) LS-C145771

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa101-150) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

ITM2C Antibody (aa101-150, HRP) LS-C446808

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa101-150) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

ITM2C Antibody (aa101-150, Biotin) LS-C446806

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa101-150) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

ITM2C Antibody (aa101-150, FITC) LS-C446807

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa101-150) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ITM2C Antibody (aa27-55) LS-C159944

Antibody:

ITM2C Rabbit anti-Human Polyclonal (aa27-55) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

ITM2C Antibody LS-C308552

Antibody:

ITM2C Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

Select

Human ITM2C Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69481

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.8 kDa

Price:

20 µg/$1,107

Select

Human ITM2C Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145196

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

53.7 kDa

Price:

50 µg/$419

Select

ITM2C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121411

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.7 kDa

Price:

100 µg/$494

Select

ITM2C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121409

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.8 kDa

Price:

100 µg/$494

Select

ITM2C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101981

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30 kDa

Price:

100 µg/$494

Select

Human ITM2C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84752

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30 kDa

Price:

20 µg/$150

Select

Human ITM2C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84751

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.7 kDa

Price:

20 µg/$150

Select

Human ITM2C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84750

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.8 kDa

Price:

20 µg/$150

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