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Catalog Number Size Price
LS-C64374-1 1 ml $995 
Antibody

Monoclonal Mouse anti‑Human Cytokeratin 8+18 Antibody (aa353‑367, IHC, WB) LS‑C64374

Monoclonal Mouse anti‑Human Cytokeratin 8+18 Antibody (aa353‑367, IHC, WB) LS‑C64374

Antibody:
Cytokeratin 8+18 Mouse anti-Human Monoclonal (aa353-367) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$995
LS-C64374-1
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
Cytokeratin 8+18 Mouse anti-Human Monoclonal (aa353-367) Antibody
Application:
IHC, IHC-P, IHC-Fr, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Cytokeratin 8+18 antibody LS-C64374 is an unconjugated mouse monoclonal antibody to human Cytokeratin 8+18 (aa353-367). Validated for IHC and WB.
Target
Human Cytokeratin 8+18
Synonyms
KRT8/KRT18 | CK8 / CK18
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Purification
Ascites
Modifications
Unmodified
Immunogen
Isolated from human breast cancer carcinoma cell line MCF-7.
Epitope
aa353-367
Specificity
Species cross-reactivity: Human, No significant reaction with mouse or rat. Recognizes all simple epithelia including glandular epithelia. It does not react with stratified squamous epithelium. Useful for the differentiation between carcinomas and lymphomas. This clone is directed against the 52.2kD cytokeratin 8 (originally reported also to 45kD cytokeratin 18) in immunoblot. Epitope has been mapped to aa353-367 on alpha helical rod domain of cytokeratin 8.
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Suitable for use in Western Blot and Immunohistochemistry (frozen and paraffin-embedded tissue, Proteolytic treatment with pepsin or pronase). Immunohistochemistry: 1:5-1:10, dilute immediately before use. Positive control: Glandular epithelium.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/25/2024