POLR3B

polymerase (RNA) III (DNA directed) polypeptide B

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

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Products

Antibodies (24)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (24)

Recombinant (1)

Target

POLR3B (27)

Reactivity

Human (19)

Mouse (15)

Rat (7)

Bat (3)

Bovine (4)

Chicken (3)

Chimpanzee (3)

Dog (4)

Drosophila (3)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (4)

Orangutan (3)

Pig (4)

Rabbit (4)

Xenopus (3)

Zebrafish (4)

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Application

IHC (5)

IHC-P (2)

WB (20)

ELISA (11)

IF (1)

IP (1)

Peptide-ELISA (2)

Host

rabbit (24)

Isotype

IgG (21)

Clonality

polyclonal pc (24)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (13)

Epitope

aa330-359 (7)

aa866-915 (4)

290-370 aa, Internal (1)

Internal (1)

aa1083-1133 (1)

aa321-370 (1)

Publications

No (27)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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POLR3B Antibody (aa321-370) LS-C119918

Antibody:

POLR3B Rabbit anti-Human Polyclonal (aa321-370) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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POLR3B Antibody (290-370 aa, Internal) LS-C385582

Antibody:

POLR3B Rabbit anti-Human Polyclonal (290-370 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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POLR3B Antibody LS-C178484

Antibody:

POLR3B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

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POLR3B Antibody LS-C672388

Antibody:

POLR3B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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POLR3B Antibody (HRP) LS-C672390

Antibody:

POLR3B Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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POLR3B Antibody (Biotin) LS-C672391

Antibody:

POLR3B Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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POLR3B Antibody (FITC) LS-C672389

Antibody:

POLR3B Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

POLR3B Antibody (aa1083-1133) LS-C288630

Antibody:

POLR3B Rabbit anti-Human Polyclonal (aa1083-1133) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

POLR3B Antibody LS-C801808

Antibody:

POLR3B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

POLR3B Antibody (Internal) LS-C368904

Antibody:

POLR3B Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Zebrafish, Pig, Rat, Rabbit, Mouse, Dog, Bovine, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

POLR3B Antibody (aa330-359) LS-C324173

Antibody:

POLR3B Rabbit anti-Human Polyclonal (aa330-359) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

POLR3B Antibody (aa330-359, Biotin) LS-C266697

Antibody:

POLR3B Rabbit anti-Mouse Polyclonal (aa330-359) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

POLR3B Antibody (aa330-359, FITC) LS-C266698

Antibody:

POLR3B Rabbit anti-Mouse Polyclonal (aa330-359) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

POLR3B Antibody (aa330-359, APC) LS-C266695

Antibody:

POLR3B Rabbit anti-Mouse Polyclonal (aa330-359) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

POLR3B Antibody (aa330-359, Azide-free, HRP) LS-C266699

Antibody:

POLR3B Rabbit anti-Mouse Polyclonal (aa330-359) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

POLR3B Antibody (aa330-359, PE) LS-C266700

Antibody:

POLR3B Rabbit anti-Mouse Polyclonal (aa330-359) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

POLR3B Antibody LS-C753470

Antibody:

POLR3B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

POLR3B Antibody LS-C824043

Antibody:

POLR3B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

POLR3B Antibody (aa866-915) LS-C81302

Antibody:

POLR3B Rabbit anti-Human Polyclonal (aa866-915) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

POLR3B Antibody (aa866-915, HRP) LS-C451635

Antibody:

POLR3B Rabbit anti-Human Polyclonal (aa866-915) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Drosophila, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

POLR3B Antibody (aa866-915, Biotin) LS-C451633

Antibody:

POLR3B Rabbit anti-Human Polyclonal (aa866-915) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Drosophila, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

POLR3B Antibody (aa866-915, FITC) LS-C451634

Antibody:

POLR3B Rabbit anti-Human Polyclonal (aa866-915) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Drosophila, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

POLR3B Antibody (aa330-359) LS-C163856

Antibody:

POLR3B Rabbit anti-Human Polyclonal (aa330-359) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

POLR3B Antibody LS-C747750

Antibody:

POLR3B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

POLR3B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111999

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

127.6 kDa

Price:

100 µg/$494

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