Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat, Cat, Rabbit (tested or 100% immunogen sequence identity)
IHC - Frozen
Western blot (1:500)
Specificity and Use
CYP4A24 antibody was raised against synthetic peptide corresponding to aa 431-445 of rat cytochrome P450 (4A isoforms).
Recognizes rat, rabbit and feline 4A2 isoform and to a lesser extent isoforms 4A1 and 4A3. Detects a band of ~50kD by Western blot. Also detects a slightly larger band representing isoforms 4A1 and 4A3.
Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry (frozen): 1:100. Western Blot: 1:500.
PBS, 0.05% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C