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CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: cytochrome P450, family 21, subfamily A, polypeptide 2
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP21A2, 21-OHase, CAH1, CYP21B, Cytochrome P450-C21, Cytochrome P450 21, Cytochrome P450 XXI, p450c21B, CA21H, CYP21, Cytochrome P-450c21, Cytochrome P450-C21B, Steroid 21-hydroxylase, Steroid 21-monooxygenase
Target Sequences: NM_000500 NP_000491.4 P08686

☰ Filters
Antibodies (50)
Proteins (12)
ELISA Kits (8)
Cell-Based (1)
Over-Expression Lysate (4)
Primary (50)
Recombinant (8)
Sandwich (7)
CYP21A2 (70)
Human (45)
Mouse (9)
Rat (17)
Chicken (1)
Chimpanzee (3)
Monkey (2)
Porcine (1)
Rabbit (1)
IHC (12)
IHC-P (8)
WB (49)
Flo (1)
ELISA (11)
ICC (1)
IF (5)
Peptide-ELISA (3)
rabbit (50)
Product Group
IHCPlus (3)
IgG (14)
polyclonal pc (50)
96-Well Microplate (1)
96-Well Strip Plate (7)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (21)
aa106-389 (8)
aa200-414 (8)
aa37-264 (8)
aa160-188 (7)
Internal (5)
aa314-363 (4)
120-200 aa, Internal (1)
Phe177 (1)
aa151-200 (1)
aa216-246 (1)
aa59-87 (1)
No (70)
Adherent Cell Cultures (1)
Cell Lysates (1)
Plasma (2)
Serum (2)
Tissue Homogenates (2)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His-T7 (3)
Myc-DDK (Flag) (5)
Human (8)
Mouse (1)
Rat (1)
293T Cells (2)
E. coli (5)
HEK 293 Cells (3)
Yeast (1)
Purified (2)
CYP21A2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CYP21A2 Rabbit anti-Human Polyclonal (aa216-246) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
CYP21A2 Antibody - Anti-CYP21A2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CYP21A2 Rabbit anti-Human Polyclonal (aa151-200) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
CYP21A2 Protein
Select
E. coli
6His, N-terminus
60 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CYP21A2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CYP21A2 ELISA Kit
Select
Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
CYP21A2 Antibody - Immunohistochemical analysis of Cytochrome P450 21A2 staining in human liver formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CYP21A2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
CYP21A2 Antibody - Anti-CYP21A2 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP21A2 Rabbit anti-Human Polyclonal (aa314-363) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CYP21A2 Antibody - Anti-CYP21A2 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP21A2 Rabbit anti-Human Polyclonal (aa314-363) (HRP) Antibody
Human, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CYP21A2 Antibody - Anti-CYP21A2 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP21A2 Rabbit anti-Human Polyclonal (aa314-363) (Biotin) Antibody
Human, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CYP21A2 Antibody - Anti-CYP21A2 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP21A2 Rabbit anti-Human Polyclonal (aa314-363) (FITC) Antibody
Human, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CYP21A2 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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CYP21A2 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CYP21A2 Antibody - Western blot of recombinant CYP21A2.
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CYP21A2 Rabbit anti-Mouse Polyclonal (aa37-264) (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557
CYP21A2 Antibody - Western blot of recombinant CYP21A2.
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CYP21A2 Rabbit anti-Mouse Polyclonal (aa37-264) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
CYP21A2 Antibody - Western blot of CYP21A2 antibody
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CYP21A2 Rabbit anti-Human Polyclonal (120-200 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CYP21A2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST, N-terminus
82.9 kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CYP21A2 Antibody - Western blot of CYP21A2 antibody
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CYP21A2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CYP21A2 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
CYP21A2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CYP21A2 Antibody - Immunohistochemical analysis of Cytochrome P450 21A2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
CYP21A2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Select
CYP21A2 Rabbit anti-Human Polyclonal (Phe177) Antibody
Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
CYP21A2 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using CYP21A2 Polyclonal Antibody at dilution of 1:60.
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CYP21A2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
CYP21A2 Rabbit anti-Human Polyclonal (aa160-188) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CYP21A2 Rabbit anti-Human Polyclonal (aa160-188) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
CYP21A2 Rabbit anti-Human Polyclonal (aa160-188) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
CYP21A2 Antibody - Western blot of CYP21A2 antibody
Select
CYP21A2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CYP21A2 Antibody - Western blot analysis of extracts from 293 cells, using Cytochrome P450 21A2 antibody.
Select
CYP21A2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 70 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).