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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTNNA3 / Alpha‑3 Catenin Antibody (aa164‑177) LS‑C12442 Best Seller
Alpha-3 Catenin antibody LS-C12442 is an unconjugated mouse monoclonal antibody to human Alpha-3 Catenin (CTNNA3). Validated for ICC, IF, IHC, IP and WB.
Antibody
Catalog
Size
Price
LS-C12442-100
100 µg
$560

Popular CTNNA3 / Alpha-3 Catenin Products

Antibody
Species: Human
Applications: IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA

Product Description

Alpha-3 Catenin antibody LS-C12442 is an unconjugated mouse monoclonal antibody to human Alpha-3 Catenin (CTNNA3). Validated for ICC, IF, IHC, IP and WB.
About CTNNA3 / Alpha-3 Catenin
CTNNA3 / Alpha-3 Catenin is a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. Q9UI47 NM_013266 NP_037398.2

CTNNA3 Antibody, Alpha-T-catenin Antibody, Cadherin-associated protein Antibody, Catenin alpha-3 Antibody, Alpha T-catenin Antibody, Alpha-catenin-like protein Antibody, VR22 Antibody


Specifications

Target
Human CTNNA3 / Alpha-3 Catenin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Dog, Rabbit (at least 90% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC (1:12)
  • ICC
  • Immunofluorescence
  • Western blot (1:50 - 1:500)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide corresponding to aa164-177 of the human alpha T Catenin protein including an additional N-terminal cysteine, coupled to KLH [C-VANKSDLQKTYQKL]. Percent identity by BLAST analysis: Human, Monkey (100%); Marmoset, Panda, Dog, Rabbit (93%); Mouse, Bovine (86%).
Epitope
aa164-177
Specificity
Recognizes human alpha T Catenin. Epitope is located between residues 164-177. Does not cross-react with alpha E Catenin or alpha N Catenin.
Usage
Suitable for use in Immunofluorescence, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry and Western Blot. Immunofluorescence: Acetone-fixed cells. Immunocytochemistry: Methanol and paraformaldehyde-fixed cells, followed by permeabilization in 0.2% Triton X-100 for 2 min. Immunohistochemistry: 1:12.5-1:100; Avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent. Western Blot: 1:50-1:500.
Presentation
PBS, pH 7.2, 0.09% Sodium Azide, 40% Glycerol
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/16/2018

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