Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Frozen, ICC, Western blot, Immunoprecipitation
Cat CSPG4 / NG2
Cat (tested or 100% immunogen sequence identity)
IHC - Frozen
Western blot (1:5000)
Specificity and Use
CSPG4 / NG2 antibody was raised against feline brain proteoglycans.
Chondroitin sulfate proteoglycan.
Immunohistochemistry: 1:2000 on 4% paraformaldehyde fixed frozen tissue. Immunocytochemistry: 1:500 on primary cultures of neurons. Western Blot: 1:5000 recognizes a band at 680kD. Immunoprecipitation.
Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity.