Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse (tested or 100% immunogen sequence identity)
Chicken (at least 90% immunogen sequence identity)
Western blot (1 - 3 µg/ml)
Specificity and Use
CSMD1 antibody was raised against synthetic peptide C-KGVREVNETVTKTP from an internal region of human CSMD1 (NP_150094.4). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Panda, Bovine, Dog, Horse, Opossum, Platypus (100%); Chicken, Lizard (93%).
Western Blot: Approx 150kD band observed in Human Brain (Cerebellum) lysates (calculated MW of 389kD according to NP_150094.4). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Kraus et al, J Immunol. 2006 Apr 1;176(7):4419-30. PMID: 16547280). Recommended concentration: 1-3 ug/ml.