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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CRYAA / Alpha A Crystallin Antibody LS‑C22441
Antibody
Alpha A Crystallin antibody LS-C22441 is an unconjugated rabbit polyclonal antibody to bovine Alpha A Crystallin (CRYAA). Validated for WB.
Catalog
Size
Price
LS-C22441-50
50 µl
Unavailable
LS-C22441-200
200 µl
Unavailable

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Product Description

Alpha A Crystallin antibody LS-C22441 is an unconjugated rabbit polyclonal antibody to bovine Alpha A Crystallin (CRYAA). Validated for WB.
About CRYAA / Alpha A Crystallin
Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. P02489 NM_000394 NP_000385.1

CRYAA Antibody, Alpha-crystallin A chain Antibody, Crystallin, alpha A Antibody, CRYA1 Antibody, Crystallin, alpha-1 Antibody, Heat shock protein beta-4 Antibody, HSPB4 Antibody


Specifications

Target
Bovine CRYAA / Alpha A Crystallin
Host
Rabbit
Reactivity
Bovine (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot
Specificity
The antibody Detects a ~20kD protein, corresponding to the apparent molecular mass of alphaA-crystallin on SDS-PAGE immunoblots, in samples from bovine. There is no reactivity with purified beta-crystallin nor alphaB-crystallin.
Usage
Western Blot (Colorimetric) 1:1000. Positive control: Bovine alphaA-Crystallin Protein.
Presentation
Serum.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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