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CREBH / CREB3L3
cAMP responsive element binding protein 3-like 3
Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression.
| Gene Name: | cAMP responsive element binding protein 3-like 3 |
| Synonyms: | CREB3L3, CREB-H, HYST1481, Transcription factor CREB-H, CREBH |
| Target Sequences: | NM_032607 NP_115996.1 Q68CJ9 |
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