Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal to Mouse COL1A1 / Collagen I Alpha 1
Mouse, Human, Rat
IHC - Paraffin, IHC - Frozen, ICC, Western blot
Rabbit Polyclonal to Human COL1A1 / Collagen I Alpha 1
Human, Monkey, Bat, Bovine, Dog, Chicken
Human COL1A1 / Collagen I Alpha 1
Human, Monkey, Bat, Bovine, Dog, Chicken (tested or 100% immunogen sequence identity)
Hamster (at least 90% immunogen sequence identity)
Protein G purified
Specificity and Use
Synthetic peptide from human COL1A1. Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Elephant, Panda, Bat, Bovine, Dog, Chicken, Lizard (100%); Hamster, Opossum (93%); Mouse, Rat (86%).
KLH conjugated synthetic peptide comprising amino acids 34 - 47 [PQPPQEKAHDGGRY] of the human collagen alpha 1 type I (COL1A1) protein.
PBS, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
COL1A1 Antibody, Alpha-1 type I collagen Antibody, Collagen alpha 1 chain type I Antibody, Collagen alpha-1(I) chain Antibody, Collagen, type I, alpha 1 Antibody, Collagen I Antibody, Pro-alpha-1 collagen type 1 Antibody, OI4 Antibody
COL1A1 / Collagen I Alpha 1 is the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis.