Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Gibbon, Monkey, Mouse, Rat, Dog, Guinea pig, Horse
Mouse Monoclonal (IgG1) to Human CHST15
Western blot, ELISA
Human (tested or 100% immunogen sequence identity)
Protein G purified
Western blot (1 - 2 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
CHST15 antibody was raised against nS0-derived rhGaINAc4S-6ST. (aa 99 - 561).
Recognizes human GalNAc4S-6ST.
Suitable for use in Direct ELISA and Western Blot. Direct ELISA: 0.5-1.0 ug/ml detection limit for rhGaINAc4S-6ST is ~10 ng/well. Western Blot: 1-2 ug/ml detection limit for rhGaINAc4S-6ST is ~5 ng/lane under non-reducing and reducing conditions.
Lyophilized from PBS, 5% trehalose. Reconstitute, 200 ul sterile 40-50% glycerol, PBS.
Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO4) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate.