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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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CHRM3 / M3 Antibody (aa580‑589) LS‑C9136
Antibody
M3 antibody LS-C9136 is an unconjugated rabbit polyclonal antibody to human M3 (CHRM3). Validated for ICC and WB.
Catalog
Size
Price
LS-C9136-100
100 µl
Unavailable

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Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

M3 antibody LS-C9136 is an unconjugated rabbit polyclonal antibody to human M3 (CHRM3). Validated for ICC and WB.
About CHRM3 / M3
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. P20309 NM_000740 NP_000731.1

CHRM3 Antibody, M3 Antibody, Muscarinic receptor M3 Antibody, Muscarinic M3 receptor Antibody, EGBRS Antibody, HM3 Antibody, M3 muscarinic receptor Antibody


Specifications

Target
Human CHRM3 / M3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Delipidated and defibrinated
Modifications
Unmodified
Applications
  • ICC (1:2500)
  • Western blot (1:500)
Immunogen
CHRM3 / M3 antibody was raised against a peptide analogue of the carboxyl terminal of the Muscarinic M3 receptor covalently attached to a carrier protein.
Epitope
aa580-589
Specificity
M3 Muscarinic Receptor (580-589) 100% M3 Muscarinic Receptor 70% M1 Muscarinic Receptor (451-460) 0% M1 Muscarinic Receptor 0% M2 Muscarinic Receptor (457-466) 0% M2 Muscarinic Receptor 0% M4 Muscarinic Receptor (469-478) 0% M4 Muscarinic Receptor 0% M5 Muscarinic Receptor (419-531) 0% M5 Muscarinic Receptor 0%.
Usage
Suitable for Immunocytochemical and Western Blot detection of the receptor. Immunocytochemistry: 1:2500. This product has been found to stain PLP fixed rat brain sections known to express the muscarinic M3 receptor using ABC techniques. Western Blot: 1:500 (Whole rat brain homogenate).
Presentation
Lyophilized.
Reconstitution
100 µl deionized water
Storage
Short term: -20°C; Long term: -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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