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Anti-CENPF / CENP-F Antibody (aa1759-2093, clone 4H9) LS-C53345

Catalog Size Price
LS-C53345-50 50 µg Unavailable

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100% Guaranteed
Mouse Monoclonal [clone 4H9] (IgG2a) to Human CENPF / CENP-F
IHC, Western blot, Immunoprecipitation


Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [4H9]
Protein G purified


  • IHC
  • Western blot
  • Immunoprecipitation

Specificity and Use

CENPF / CENP-F antibody was raised against gST fusion protein expressed in E. coli corresponding to aa 1759-2093 of human mitosin.
mitosin, a 350 kD phosphoprotein that is specifically involved in mitotic-phase progression. Mitosin is expressed throughout S, G2, and M phases of the cell cycle, but is absent in G0 and G1. It associates with the mitotic apparatus during M-phase and is redistributed from the nucleus to the centromere, spindle, and midbody during M-phase progression. Its usefulness as a proliferation marker is under active investigation


For research use only.


P49454 NM_016343 NP_057427.3

CENPF Antibody, AH antigen Antibody, Centromere protein F Antibody, CENF Antibody, CENP-F Antibody, Kinetochore protein CENPF Antibody, Mitosin Antibody, CENP-F kinetochore protein Antibody, Hcp-1 Antibody, PRO1779 Antibody

Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation.

Requested From: 
Date Requested: 3/23/2018

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