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CELF2 / CUGBP2

CUGBP, Elav-like family member 2

RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle. Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Promotes inclusion of exonS 21 and exclusion of exon 5 of the NMDA receptor R1 pre-mRNA. Involved in the apoB RNA editing activity. Increases COX2 mRNA stability and inhibits COX2 mRNA translation in epithelial cells after radiation injury (By similarity). Modulates the cellular apoptosis program by regulating COX2-mediated prostaglandin E2 (PGE2) expression (By similarity). Binds to (CUG)n triplet repeats in the 3'-UTR of transcripts such as DMPK. Binds to the muscle-specific splicing enhancer (MSE) intronic sites flanking the TNNT2 alternative exon 5. Binds preferentially to UG-rich sequences, in particular UG repeat and UGUU motifs. Binds to apoB mRNA, specifically to AU-rich sequences located immediatly upstream of the edited cytidine. Binds AU-rich sequences in the 3'-UTR of COX2 mRNA (By similarity). Binds to an intronic RNA element responsible for the silencing of exon 21 splicing (By similarity). Binds to (CUG)n repeats.

Gene Name: CUGBP, Elav-like family member 2
Synonyms: CELF2, BRUNOL3, CELF-2, Bruno-like protein 3, CUG-BP2, CUGBP2, ETR-3, HNAPOR, NAPOR, RNA-binding protein BRUNOL-3, NAPOR-2, ETR3
Target Sequences: NM_006561 NP_006552.3 O95319

☰ Filters
Antibodies (33)
Proteins (10)
Over-Expression Lysate (6)
Primary (33)
Recombinant (4)
CELF2 / CUGBP2 (43)
Human (33)
Mouse (14)
Rat (8)
Bat (6)
Bovine (9)
Chicken (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (6)
Horse (6)
Monkey (6)
Orangutan (6)
Rabbit (6)
Xenopus (6)
Zebrafish (6)
IHC (12)
IHC-P (10)
WB (30)
ELISA (12)
IF (2)
IP (2)
Peptide-ELISA (1)
rabbit (33)
Product Group
IHCPlus (2)
IgG (28)
polyclonal pc (33)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (11)
aa481-508 (7)
N-Terminus (4)
aa112-161 (4)
aa73-122 (4)
No (42)
Yes (1)
GST (2)
Myc-DDK (Flag) (8)
Human (7)
293T Cells (3)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Purified (1)
CELF2 / CUGBP2 Antibody - CELF2 / CUGBP2 antibody ARP40323_T100-NP_006552-CUGBP2 (CUG triplet repeat, RNA binding protein 2) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa73-122) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
CELF2 / CUGBP2 Antibody - CELF2 / CUGBP2 antibody ARP40323_T100-NP_006552-CUGBP2 (CUG triplet repeat, RNA binding protein 2) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa73-122) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Rat, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
CELF2 / CUGBP2 Antibody - CELF2 / CUGBP2 antibody ARP40323_T100-NP_006552-CUGBP2 (CUG triplet repeat, RNA binding protein 2) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa73-122) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Rat, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
CELF2 / CUGBP2 Antibody - CELF2 / CUGBP2 antibody ARP40323_T100-NP_006552-CUGBP2 (CUG triplet repeat, RNA binding protein 2) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa73-122) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Rat, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
CELF2 / CUGBP2 Antibody - Immunohistochemistry Dilution at 1:600 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
CELF2 / CUGBP2 Antibody - Anti-CELF2 / CUGBP2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CELF2 / CUGBP2 Antibody - Anti-CELF2 / CUGBP2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Bovine, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CELF2 / CUGBP2 Antibody - Anti-CELF2 / CUGBP2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Bovine, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CELF2 / CUGBP2 Antibody - Anti-CELF2 / CUGBP2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Bovine, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CELF2 / CUGBP2 Antibody - Anti-CELF2 / CUGBP2 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa481-508) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
Select
CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa481-508) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa481-508) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa481-508) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa481-508) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa481-508) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa481-508) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
CELF2 / CUGBP2 Antibody - Western blot analysis of extracts of K562 cells using CUGBP2 antibody. The lane on the left was treated with blocking peptide.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
CELF2 / CUGBP2 Antibody - Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CELF2 / CUGBP2 Rabbit anti-Human Polyclonal (aa112-161) Antibody
Human
WB
Unconjugated
100 µl/$424
CELF2 / CUGBP2 Antibody - Western blot analysis of extracts of various cells.
Select
CELF2 / CUGBP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-25 of 43 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).