Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Human CEA / Carcinoembryonic Antigen
IHC - Paraffin, IHC - Frozen, Western blot
Human CEA / Carcinoembryonic Antigen
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Frozen
Specificity and Use
Isolated from human colon carcinoma cells.
Directed against a single band of 180kD of human carcinoembryonic antigen (CEA) and shows no cross-reactivity neither with biliary glycoprotein (BGP) nor with non-specific cross-reacting antigen (NCA). Recommended for Colonic carcinoma. Species cross-reactivity: Human.
Suitable for use in Western Blot and Immunohistochemistry (frozen sections, cell preparations and paraffin sections, no pretreatment required). Immunohistochemistry: 1:5-1:10; Incubation Time 1 hr at room temperature.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.
About CEA / Carcinoembryonic Antigen
Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore CEA is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical tests. Serum levels can also be elevated in heavy smokers.