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Anti-CD119 / IFNGR1 Antibody (Extracellular Domain) LS-C7627


Wt. Vol. Conc. Price
100 µg - - $650
Inquire for larger quantities

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Goat Polyclonal (IgG) to Human CD119 / IFNGR1
IHC, ICC, Western blot, ELISA, Functional Assay, Neutralization


Human CD119 / IFNGR1
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC (15 µg/ml)
  • ICC
  • Western blot (0.1 - 0.2 µg/ml)
  • Functional Assay
  • Neutralization

Specificity and Use

CD119 / IFNGR1 antibody was raised against recombinant, human Interferon gamma receptor chain 1, NS0-derived, extracellular domain.
Extracellular Domain
Binds to and neutralizes human Interferon gamma receptor 1, 15.756kD. Blocks cell surface human Interferon gamma receptor 1-mediated bioactivity of recombinant human Interferon gamma receptor 1. In direct ELISA and Western Blot, does not cross-react with human Interferon gamma receptor chain2.
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Neutralization. Neutralization of Human IFN-g R1 Bioactivity: The exact concentration of antibody required to neutralize rhIFN-g R1-mediated bioactivity is dependent on the cytokine concentration, cell type, growth conditions and the type of activity studied. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. The ND50 is ~0.5-2 ug/ml in the presence of 2 ng/ml of rhIFN-g, using a confluent culture of HeLa cells. ELISA (Direct): 0.5-1 ug/ml. The detection limit for rhIFN-g R1 is ~0.3 ng/well. Western Blot: 0.1-0.2 ug/ml. The detection limit for is ~5 ng/lane under non-reducing and reducing conditions. Immunohistochemistry: 15 ug/ml. Detects IFN-g R1 in human PBMC's (peripheral blood mononuclear cells) (fluorescence immunocytochemistry).


PBS, pH 7.4, 5% trehalose. No preservative added.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CD119 / IFNGR1

P15260 NM_000416 NP_000407.1

IFNGR1 Antibody, AVP, type 2 Antibody, Antiviral protein, type 2 Antibody, CD119 Antibody, CD119 antigen Antibody, IFNGR Antibody, IFN-gamma receptor 1 Antibody, IFN-gamma-R1 Antibody, Immune interferon receptor 1 Antibody, Interferon gamma receptor 1 Antibody, CDw119 Antibody

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

Requested From: United States
Date Requested: 10/26/2016

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